Indications & Usage
Trophoblastic neoplasms (choriocarcinoma, chorioadenoma destruens, and hydatiform mole), leukemia. Rheumatoid arthritis. Severe, uncontrolled psoriasis which is not responsive to other therapy. 

Dosage & administration
▷The usual dosage: 1∼3 tablets daily. 

▷The maximum dosage: 6 tablets daily.

▷Rheumatoid arthritis: 7.5∼20 mg once weekly or every 12 hours in three divided doses, orally.